for the National Surgical Adjuvant Breast and Bowel Project Technical outcomes of sentinel-lymph-node resection and conventional axillary-lymph-node dissection in patients with clinically node-negative breast cancer: results from the NSABP B-32 randomised phase III trial. Krag DN, Anderson SJ, Julian TB, et al.Diseases of the Breast, 5th edition, Lippincott Williams & Wilkins, 2014. Chapter 38: Axillary Dissection, in Harris JR, Lippman ME, Morrow M, Osborne CK. (blue dye, radioactive tracer or combined technique)Īccuracy in Predicting Lymph Node Status, Sensitivity %īlue dye alone, radioactive tracer or combined technique Table note: Sensitivity in the table below measures how accurately sentinel node biopsy identified lymph node status.įor example, a sensitivity of 90 percent means 90 percent of the people the sentinel node biopsy identified as having positive lymph nodes did, in fact, have cancer in their lymph nodes when checked with axillary dissection. Study selection criteria: Randomized clinical trials with at least 200 participants and meta-analyses. Learn about the strengths and weaknesses of different types of studies. Learn about lymph node status and staging. Learn about lymph node status and breast cancer prognosis (chances of survival). Learn more about sentinel node biopsy and axillary dissection. Has fewer side effects (such as infection, lymphedema and nerve damage).Now, only some people who have positive sentinel lymph nodes will need an axillary dissection.Ĭompared to axillary dissection, sentinel node biopsy: In the past, lymph nodes were assessed using axillary dissection. If there’s cancer in the lymph nodes, sentinel node biopsy will find it over 90 percent of the time. Introduction: Sentinel node biopsy is the main way to check if breast cancer has spread to the lymph nodes in the underarm area. However, to get the most out of the tables, it’s important to understand some key concepts. Summary tables are a useful way to look at the science behind many breast cancer guidelines and recommendations. This summary table contains detailed information about research studies.
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